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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Genetic alterations that deregulate RB and PDGFRA signaling pathways drive tumor progression in IDH2-mutant astrocytoma

Fig. 1

Clinical characteristics of IDH2-mutant astrocytoma patient. A Magnetic resonance imaging showing FLAIR (left), T2-weighted (middle), and gadolinium-enhanced T1-weighted (right) images for initial tumor (YMG25P, upper panel) and recurrent tumor (YMG25R, lower panel). B Hematoxylin and eosin staining (upper) and Ki-67 immunohistochemistry (lower) for YMG25P (left) and YMG25R (right) tumors. Bars, 50 μm. C Sanger sequencing indicating IDH2 (c.515G > A, R172K) and TP53 (c.742C > T, R248W) mutation in YMG25P (upper) and YMG25R (lower)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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