Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains

Table 1 Clinical and demographic data of all cases within the study

	Number of cases (n)	Age onset (years)		Age of death (years)		Female		Male
		Age	SD	Age	SD	n	%	n	%
AD	282	67.0	11.2	78.1	11.6	152	53.9	130	46.1
CJD	181	54.2	19.6	55.1	19.2	96	53.0	85	47.0
Control	351			78.1	12.0	196	55.8	155	44.2
DLB-PD	89	63.9	10.3	75.1	8.5	31	34.8	58	65.2
FTD-ALS	236	58.9	11.2	64.4	11.5	98	41.5	137	58.1
Young Controls	110			41.4	9.7	30	27.3	80	72.7
Other disorders (See Additional file 1: Tables S1-S8)	114	60.3	21.5	72.7	16.7	46	40.3	68	59.7
Mean		60.6	17.2	69.0	17.4		43.9		56.1
Total	1363					598		765

Key: AD Alzheimer’s disease, CJD Creutzfeldt Jacob Disease, DLB-PD Dementia with Lewy Bodies or Parkinson’s disease, FTD-ALS Frontotemporal Dementia or Amyotrophic Lateral Sclerosis. Information about Other disorders can be seen in Additional file 1: Table S2

ISSN: 2051-5960