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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation

Fig. 5

Golgi morphology in the oligomerization and aggregation models. a-b Representative pictures of transfected cells with the BiFC system. We analyzed and categorized transfected cells in different categories. Scale bar: 30 μm. b WT aSyn resulted in an increased percentage of cells with fragmented Golgi morphology when compared with the empty vector and with cells expressing the A53E mutant. c-d Representative pictures of transfected cells with SynT + Synphilin-1. Scale bar: 30 μm. d In the presence of A53E SynT, the Golgi is more diffuse when compared with the control and with WT SynT. n = 3

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