Fig. 2
From: Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection
The probability that the PET image is interpreted as positive increases with cortical neuritic plaque burden. Panel a . The probability (0-1) of a PET positive assessment increases with CERAD neuritic plaque frequency (N = 106). Panel b . The probability of PET positive image assessment by neocortical regional mCERADSOT score (N = 424, 4 neocortical regions per case; frontal, temporal, parietal and posterior cingulate/precuneus). Panel c & d. The probability of PET positive image assessment increases by AD diagnosis against the NIA-AA (Panel c) and NIA-RI criteria (Panel d). For all panels, boxes represent mean +/- 1 standard error and whiskers represent 95% confidence interval. Open circles represent outlier values and asterisks represent extreme values (see Materials and methods for details)