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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice

Fig. 5

EGF has no effect on Aβ levels. a, b ThioS plaque and extracellular Aβ levels were the same in EGF and VC treated E4FADF mice (IHC analysis). c, d When assessed biochemically, EGF also had no effect on soluble, detergent soluble or insoluble Aβ42 levels in the cortex of hippocampus (ELISA). e Soluble oAβ levels were unaffected by EGF treatment (ELISA). f, g ApoE levels were unaffected by EGF treatment (ELISA). n = 8 per group. Data expressed as mean +/− S.E.M. Data non-significant by Students t test

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Acta Neuropathologica Communications

ISSN: 2051-5960

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