Fig. 1

Neurodegenerative Disease Pathology in the Occipital Lobe in Dementia with Lewy Bodies. Representative staining for α-synuclein, Aβ (4G8), and hyperphosphorylated tau (AT8) in primary visual (BA17), secondary visual (BA18), and lateral occipital cortices (BA37) in DLB cases. An absence of α-synuclein pathology was seen in BA17, although increasing levels of α-synuclein could be seen in BA18 and in BA37. Similarly, an absence of AT8 (hyperphosphorylated tau) staining was seen in BA17 but increasing levels were seen in BA18 and BA37. Aβ (4G8) pathology was present in all cortical regions examined. Photomicrographs were taken at x2.5 magnification (upper rows) or at x40 magnification (lower rows) with scale bars at 1000 μm (upper rows) or 50 μm (lower rows)