Fig. 1
From: Clobetasol promotes remyelination in a mouse model of neuromyelitis optica
Evaluation of potential remyelinating drugs in primary cultures of oligodendrocyte precursor cells (OPCs). a. Representative immunofluorescence (Olig2, red; MBP, green) of OPC cultures treated for 6 days with vehicle (DMSO), T3 (30 nM) as positive control, and indicated drugs (GC-1 30 nM; benztropine, clemastine and fasudil 1 μM; others 5 μM) (top). Percentage of MBP-positive cells, with cells graded for degree of maturation (mean ± S.E., n = 18 fields in three wells, ** P < 0.01) (bottom). b. Clobetasol concentration-dependence study for OPC cultures treated for 6 days (top). Percentage of MBP-positive cells (mean ± S.E., n = 6 fields in three wells, ** P < 0.01) (bottom)