Fig. 2

T. gondii infection induces histopathological changes and activation of microglia. a, a’ Hematoxylin and eosin (H&E) stained coronal sections from (a) non-infected and (a’) T. gondii infected 5xFAD mice. * denotes meningeal infiltrates, arrows show inflammatory foci, the arrow head highlights a T. gondii cyst. The inset shows a cyst stained with an antibody against T. gondii. b–d’ Representative pictures of immunohistochemical stainings against (b, b’) Iba1, (c, c’) GFAP, and (d, d’) NeuN of coronal brain sections from (b, c, d) non-infected and (b’, c’, d’) T. gondii infected 5xFAD mice. Scale bars represent 1000 μm (left column) and 200 μm (right column)