Table 2 Endpoint titration of serially passaged MM2-sCJD prions in human or ovine PrP mice
Inoculum | Dilution | Mean incubation timea (n/n0) | |
|---|---|---|---|
| Â | Â | tg650 (human PrP) | tg338 (ovine PrP) |
MM2-sCJDb | 10−4 | 351 ± 6 (5/5) | nd |
|  | 10−5 | 441 ± 51 (3/5) | 163 ± 10 (6/6) |
|  | 10−6 | 424; 501 (2/6) | 227 ± 22 (4/6) |
|  | 10−7 | >600 (0/6) | > 500 (0/6) |
|  | 10−8 | >600 (0/6) | >500 (0/6) |