Fig. 2
From: CSF complement 3 and factor H are staging biomarkers in Alzheimer’s disease
CSF C3 and FH levels according to diagnosis in the ADNI and Emory cohorts. MCI subjects only include those whose CSF t-Tau/Aβ42 ratio is greater than 0.39. Bars represent median values with interquartile range. Univariate analyses did not show any difference in C3 and FH levels between MCI and AD (panel a), but biomarker levels were strongly influenced by age (panel b; p < 0.001 for C3, p = 0.001 for FH). MCI-Other: initial clinical diagnosis with CSF t-Tau/Aβ42 < 0.39