Table 2 DPPE, a selective ChEH ligand, significantly increased recombination in the DRG, hippocampus and olfactory bulb
From: Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis
Tissue | Saline | DPPE | p value | Analysis details |
|---|---|---|---|---|
DRG | 12.33 +/− 2.33 | 26.00 +/− 3.21 | 0.026 | Neurons per DRG whole-mount, 2 cervical DRG/ n |
Dentate gyrus | 1.17 +/− 0.44 | 8 +/− 0.58 | 0.001 | Granule cell neurons per section, 4 sections/ n, anterior dentate gyrus at the level of the median eminence |
Olfactory bulb | 2 +/− 0.58 | 12.33 +/− 1.45 | 0.003 | Granule cell neurons per 150 × 500 micron field, mid-OB |