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Table 1 Characteristics of MSA and iLBD cases used for inoculation experiments

From: Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein

Case ID

Sex (M/F)

Age at death (years)

Postmortem delay time (h)

Neurological diagnosis

Alpha-synuclein concentration in the sarkosyl-insoluble fraction (ng/ml)

Source

MSA1

F

51

48

MSA

20.99

BBCT

MSA2

M

59

32

MSA

21.52

QSBB

iLBD1

M

78

48

non-clinical

18.05

BBCM

iLBD2

F

68

48

non-clinical

8.17

BBCL

  1. MSA multiple system atrophy, iLBD incidental Lewy body disease, M male, F female, BBCT Brain Banking Center Tübingen, QSBB Queen Square Brain Bank for Neurological Disorders, BBCM Brain Banking Center Münster, BBCL Brain Banking Center Leipzig