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Table 3 Frequency of WHO criteria in the different tumor subtypes

From: Histological criteria for atypical pituitary adenomas – data from the German pituitary adenoma registry suggests modifications

 

Subgroups

All Patients

TPAs

APAs

PCAs

Total

N=

Mean

N=

Mean

N=

Mean

N=

Mean

Mitotic index (in 10 HPF)

200

1

98

7

10

3

308

3

p53 pos. Nuclei (%)

200

1

98

8

10

8

308

3

Ki-67 pos. Nuclei (%)

200

1

98

9

10

7

308

4

Growth pattern

Non invasive

77

-

8

-

0

-

85

-

Invasive

68

-

58

-

10

-

136

-

  1. Overview of metric and dichotomous parameters analyzed in the subgroups of pituitary tumors analyzed
  2. N number, HPF High power field, TPA typical pituitary adenomas, APA atypical pituitary adenomas, PCA pituitary carcinomas