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Table 1 Demographics and non-ALS pathology in 33 patients

From: TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis

Average age at death (years)

62.7 (s = 9.09)

Male/Female

n = 25/n = 8

Median duration (years)

3.1 (interquartile range, 2.2-4.8)

Brain weight (grams)

1348.6 (s = 156.97)

Any neurofibrillary pathology

n = 24

Any parenchymal amyloid

n = 9

Thal stage ≥ II

n = 7

Braak stage ≥ III1

n = 4

CERAD ≥ “moderate”

n = 2

CAA present2

n = 6

VBI present3

n = 3

LB pathology

n = 0