Figure 4

Boxplots of BMI relative to involvement of any region in the basal forebrain and/or hypothalamus (left) versus LHA (right) for patients with a BMI measure within ≤ 24 months the time of death (median interval of 3.6 months). Plots represent BMI for basal forebrain/hypothalamus (n = 29; 19 patients without TDP-43 pathology and 10 with inclusion pathology) and for patients with the LHA sampled (n = 25; 21 patients without TDP-43 pathology and 4 with inclusion pathology). There was no significant difference in BMI for patients with and without TDP-43 pathology in any component of forebrain/hypothalamus (left). For the LHA, a significant difference in BMI was identified between patients with and without TDP-43 pathology (p = 0.02). Boxplot prepared in R (R Foundation for Statistical Computing, Vienna, Austria, 2014).