| Pathological diagnosis | Age of death (y)/sex | Brain weight (g) | Duration (y) | Braak NFT stage | Clinical symptoms | Type of tau-positive inclusions investigated |
---|---|---|---|---|---|---|---|
Case 1 | Normal aging | 73/F | 1,260 | na | I | No history of dementia or motor symptoms | Pretangles, NFTs |
Case 2 | AD | 58/F | 850 | 14 | VI | Severe dementia, disorientation | Pretangles, NFTs |
Case 3 | CBD | 60/M | 1,145 | 7 | I | Supranuclear gaze palsy, frequent fall, parkinsonism, frontal signs | Pretangles, Pick-like inclusions* |
Case 4 | CBD | 70/F | 770 | 11 | III | Frontotemporal dementia, parkinsonism | Pretangles, Pick-like inclusions, ballooned neurons |