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Figure 8 | Acta Neuropathologica Communications

Figure 8

From: Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy

Figure 8

Immunohistochemistry for TPPP, synuclein and mitochondrial proteins in a familial MSA patient with homozygous COQ2 defective mutations. Immunohistochemistry in the pons of Case 11 showed numerous pα-syn-positive GCIs (a), the redistribution of TPPP (b), and DRP1 immuno-positive GCIs (arrowheads) (c). Abnormal accumulation of DRP1 (d) and TOM20 (h), colocalizing with pα-syn (e & i), can be observed in the GCI (g & k). Scale bar = 50 µm (a-c), 10 µm (d-k).

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Acta Neuropathologica Communications

ISSN: 2051-5960

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