Figure 2
From: Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies
KW1 expression reduces the viability of different Aβ(1–40) expressing fly lines. (A-C) Lifespan measurements of Aβ40 flies (filled) and KW1;Aβ40 flies (unfilled) (A), Aβ40-51D flies (filled) and KW1;Aβ40-51D flies (unfilled) (B) and Aβ40-29.1 flies (filled) and KW1;Aβ40-29.1 flies (unfilled) (C). (D) Fly viability versus Aβ concentration in the fly head. The fly viability (%) is given relative to fly lines without KW1 expression. Symbols: Filled diamond: KW1 relative to WT. Unfilled square: KW1;Aβ40-29.1 relative to Ab40-29.1. Unfilled triangle: KW1;Aβ40-51D relative to Aβ40-51D. Unfilled circle: KW1;Aβ40 relative to Aβ40. Data were fitted by linear regression (R = 0.86). For original values please refer to Table 1.