Figure 5

Proliferation analysis of LN319 glioma and HEK293T cells with and without induction of mutant IDH expression. Cell viability of LN319 glioma and HEK293T cells bearing tetracycline inducible constructs of different IDH mutations and controls 72 h after induction. Shown are the relative cell numbers compared to the corresponding uninduced controls. The significant differences are depicted in the figure with their corresponding to their p-values (* = p ≤ 0.05 and ** = p ≤ 0.01).