Figure 3From: Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol Dose response curve of rescue of axonal fragmentation by taxol. Graph shows axonal fragmentation in vehicle (control) treated cultures and those exposed to kainic acid (KA) with 10, 100, 500 and 1000Â ng/ml taxol. 100Â ng/ml taxol was sufficient to significantly protect axons from fragmentation following kainic acid exposure.Back to article page