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Table 1 Summary of ER abnormalities in Thy1.2-hVAPB transgenic lines

From: Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment

Mouse line

HA-staining

ER abnormalities

  

Tubular ER

Stacked ER

Electron dense stacked ER

hVAPB-wt

    

  VW1

+++++

-

+

+

  VW2

++++

-

+

-

  VW3

++++

-

+

-

hVAPB-P56S

    

  VM1

++

+

-

-

  VM2

+

-

-

-

  VM3

++

+

-

-

  VM5

++

+

-

-

  VM1 + VM5

+++

+

-

-

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Acta Neuropathologica Communications

ISSN: 2051-5960

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